Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 7/20 | 0.63 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | IDH2 | P48735 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MLNR | O43193 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750850 | 0.85 | DRD2 (0.63) | UBE2MDCUN1D1MEN1KMT2AKDM4E | |
| SCHEMBL24781281 | 0.83 | IDH2 (0.62) | UBE2MDCUN1D1MEN1KMT2ALMNA | |
| SCHEMBL21856366 | 0.82 | DCUN1D1 (0.49) | UBE2MDCUN1D1MEN1KMT2AROCK2 | |
| SCHEMBL12041199 | 0.81 | DCUN1D1 (0.60) | UBE2MDCUN1D1MEN1KMT2AKDM4E | |
| SCHEMBL24781034 | 0.80 | IDH2 (0.50) | UBE2MDCUN1D1MEN1KMT2ALMNA | |
| SCHEMBL18466535 | 0.80 | KDM4E (0.47) | UBE2MDCUN1D1MEN1KMT2AKDM4E | |
| SCHEMBL21958743 | 0.80 | EPHX2 (0.70) | UBE2MDCUN1D1MEN1KMT2AEPHX2 | |
| SCHEMBL12969653 | 0.80 | IDH2 (0.73) | UBE2MDCUN1D1MEN1KMT2AKDM4E | |
| SCHEMBL2575970 | 0.79 | CARM1 (0.59) | KDM4EROCK2 | |
| SCHEMBL15120074 | 0.78 | PHGDH (0.54) | KMT2ALMNAROCK2IDH2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29828-E | ANALGESICS, ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1978-11-07 | — | — | US | disclosed |