Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.59 |
| ▸ | STS | P08842 | 5/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873347 | 0.89 | HSD17B1 (0.53) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL11579497 | 0.89 | HSD17B1 (0.53) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL11577806 | 0.89 | HSD17B1 (0.56) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL1027642 | 0.88 | HSD17B1 (0.66) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL11577041 | 0.88 | HSD17B1 (0.60) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL8969620 | 0.87 | CYP19A1 (0.54) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL27645540 | 0.86 | CYP3A4 (0.65) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL28781706 | 0.84 | STS (0.62) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL2470063 | 0.83 | HSD17B1 (0.68) | CYP19A1HSD17B1STSESR1HSD17B10 | |
| SCHEMBL11879317 | 0.83 | HSD17B1 (0.68) | CYP19A1HSD17B1STSESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096253-A | 1-Oxygenated steroids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |