Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | STS | P08842 | 8/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577787 | 0.87 | CYP19A1 (0.59) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL11873347 | 0.85 | HSD17B1 (0.53) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL11579497 | 0.85 | HSD17B1 (0.53) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL11577041 | 0.83 | HSD17B1 (0.60) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL8988016 | 0.82 | CYP19A1 (0.40) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL6265194 | 0.80 | STS (0.70) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL6266355 | 0.80 | STS (0.70) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL1234807 | 0.79 | STS (0.71) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL5161530 | 0.79 | CYP19A1 (0.60) | CYP19A1HSD17B1ESR1STSCYP3A4 | |
| SCHEMBL5158357 | 0.78 | CYP19A1 (0.71) | CYP19A1HSD17B1ESR1STSCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424372-B1 | ANTIMICROBIAL COMPOSITIONS AND RELATED METHODS OF USE | JENEIL BIOSURFACTANT CO LLC (US) | 2018-01-17 | — | — | EP | claimed |
| EP-0191736-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | claimed |
| US-5554603-A | 11,17-DINITRATES; USE TO ACHIEVE ESTROGENIC EFFECT IN FEMALE MAMMALS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-09-10 | — | — | US | disclosed |
| WO-1995007925-A1 | ORALLY ACTIVE DERIVATIVES OF 1,3,5(10)-ESTRATRIENE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-03-23 | — | — | WO | disclosed |