Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129944 | 0.85 | ALDH1A1 (0.49) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7824979 | 0.85 | TTR (0.49) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27744454 | 0.83 | MEN1 (0.49) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10594916 | 0.83 | TDP1 (0.46) | KMT2AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL10616262 | 0.83 | MEN1 (0.49) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1345382 | 0.83 | MEN1 (0.44) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3584980 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19329393 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2MAPK1TP53 | |
| SCHEMBL2130850 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3584977 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113282-A | TETRANITRODIPHENYL ACETIC ACID DERIVATIVES | THE MEAD CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-3996052-A | Phototropic compounds as acid catalyst in photopolymerizing process | AMERICAN CAN COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
| US-3949143-A | Epoxy resin coatings cured with phototropic aromatic nitro compounds | AMERICAN CAN COMPANY (US) | 1976-04-06 | — | — | US | disclosed |