Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744454 | 0.87 | MEN1 (0.49) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL10616262 | 0.87 | MEN1 (0.49) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL8141315 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11577835 | 0.85 | TTR (0.46) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL10071375 | 0.84 | TTR (0.50) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL823705 | 0.81 | RECQL (0.56) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL30318004 | 0.81 | RECQL (0.56) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL6129748 | 0.81 | ALDH1A1 (0.46) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL427368 | 0.81 | ALDH1A1 (0.55) | TTRMEN1KMT2AMAPTHSPB1 | |
| SCHEMBL1220299 | 0.81 | ALDH1A1 (0.55) | TTRMEN1KMT2AMAPTHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097918-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED-2-NITRO-FLUOROBENZENES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |