Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19713194 | 0.85 | GPR35 (0.50) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL6543923 | 0.82 | PDGFRB (0.50) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL1653791 | 0.82 | GPR35 (0.47) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL27601624 | 0.82 | GPR35 (0.47) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL1625689 | 0.82 | GPR35 (0.47) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL18258894 | 0.81 | GPR35 (0.46) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL19713198 | 0.81 | GPR35 (0.46) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL19713196 | 0.80 | GPR35 (0.45) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL48359 | 0.80 | GPR35 (0.55) | GPR35TSHRL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL3206927 | 0.80 | GPR35 (0.55) | GPR35TSHRL3MBTL1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113282-A | TETRANITRODIPHENYL ACETIC ACID DERIVATIVES | THE MEAD CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |