SCHEMBL48359

SCHEMBL48359

O=C(Oc1cccc([N+](=O)[O-])c1[N+](=O)[O-])Oc1cccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.55
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 4/20 0.48
ALDH1A1 P00352 6/20 0.46
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
RECQL P46063 1/20 0.44
HSPB1 P04792 1/20 0.43
HTT P42858 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP1A2 P05177 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HPGD P15428 1/20 0.41
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3206927 0.89 GPR35 (0.55) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL48360 0.88 GPR35 (0.53) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL48361 0.88 GPR35 (0.53) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL2373772 0.86 GPR35 (0.51) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL1652615 0.86 GPR35 (0.51) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL17005575 0.86 TSHR (0.51) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL28857890 0.86 RAB9A (0.51) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL25331485 0.85 TSHR (0.50) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL11250446 0.85 GPR35 (0.50) GPR35TSHRTDP1ALDH1A1RAB9A
SCHEMBL19713194 0.85 GPR35 (0.50) GPR35TSHRTDP1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114094175-A Secondary battery 珠海冠宇电池股份有限公司 2022-02-25 CN claimed
US-8445734-B2 Photolabile protective groups for improved processes to prepare oligonucleotide arrays NIGU CHEMIE GMBH (DE) 2013-05-21 US claimed
US-5446134-A Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1995-08-29 US claimed
US-20250281634-A1 CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY TUBULIS GMBH (DE) 2025-09-11 US disclosed
EP-4554984-A1 MANNOSYLATED AMINE DEXTRAN DRUG DELIVERY VEHICLES WITH DEGRADABLE DISULFIDE/CARBONATE LINKERS TARGETING PAYLOADS TO CD206 EXPRESSING CELLS Navidea Biopharmaceuticals, Inc. (US) 2025-05-21 EP disclosed
WO-2025072355-A1 METHODS FOR AND COMPOSITIONS OF NON-PEG BIOCONJUGATES WITH ULTRA-HIGH DRUG-TO-AGENT RATIO BIOHYBRID SOLUTIONS HOLDINGS, INC. (US) 2025-04-03 WO disclosed
US-12252746-B2 Anti-CD46 antibodies and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-18 US disclosed
US-20250051577-A1 SULFORHODAMINE PHOSPHORAMIDITE DYES CEPHEID (US) 2025-02-13 US disclosed
EP-3538153-B1 ANTI-CD46 ANTIBODIES AND METHODS OF USE UNIV CALIFORNIA (US) 2024-10-09 EP disclosed
CN-118662655-A Compound, pharmaceutical composition, preparation method and application thereof 安迪高生物制药有限公司 2024-09-20 CN disclosed
EP-4429708-A1 CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY Tubulis GmbH (DE) 2024-09-18 EP disclosed
US-6030941-A FOR DELIVERY OF DRUGS AND OTHER COMPOUNDS ACROSS LIPID LAYERS AVI BIOPHARMA, INC. (US) 2000-02-29 US disclosed
EP-0966303-A2 POLYPEPTIDE CONJUGATES FOR TRANSPORTING SUBSTANCES ACROSS CELL MEMBRANES ANTIVIRALS INC. (US) 1999-12-29 EP disclosed
EP-0932391-A2 FUSOGENIC LIPOSOME COMPOSITION AND METHOD SEQUUS PHARMACEUTICALS, INC. (US) 1999-08-04 EP disclosed
WO-1998016202-A2 FUSOGENIC LIPOSOME COMPOSITION AND METHOD SEQUUS PHARMACEUTICALS, INC. (US) 1998-04-23 WO disclosed
US-5733563-A CROSSLINKED MIXTURE OF AQUEOUS SOLUTION OF POLYOXYETHYLENE GLYCOL ACTIVATED WITH 4-NITROPHENYL CHLOROFORMATE REACTIVE WITH PROTEIN ALBUMIN CONTAINING FREE ACID, HYDROXY, MERCAPTAN AND AMINE GROUPS; USED FOR CONTROLLED DRUG DELIVERY UNIVERSITE DU QUEBEC A MONTREAL (CA) 1998-03-31 US disclosed
WO-1997040854-A2 POLYPEPTIDE CONJUGATES FOR TRANSPORTING SUBSTANCES ACROSS CELL MEMBRANES ANTIVIRALS INC. (US) 1997-11-06 WO disclosed
EP-0705298-A1 ALBUMIN BASED HYDROGEL UNIVERSITE DU QUEBEC A MONTREAL (CA) 1996-04-10 EP disclosed
WO-1995015352-A1 ALBUMIN BASED HYDROGEL UNIVERSITE DU QUEBEC A MONTREAL (CA) 1995-06-08 WO disclosed
US-5221798-A Changing the regiopurity of mixtures containing 4,4'-disubstituted diphenyl carbonates AMOCO CORPORATION (US) 1993-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281634-A1 CONJUGATES COMPRISING A PHOSPHORUS (V) AND A DRUG MOIETY CALCR, BCR, PTH1R GPR35 487/4885TSHR 214/4885TDP1 2727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.