Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 13/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | YAP1 | P46937 | 1/20 | 0.55 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.55 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601573 | 0.82 | RXFP1 (0.67) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11520753 | 0.81 | LMNA (0.66) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4563522 | 0.80 | LMNA (0.57) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10597386 | 0.80 | LMNA (0.71) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9271694 | 0.80 | RXFP1 (0.70) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11579676 | 0.80 | LMNA (0.67) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10592753 | 0.79 | LMNA (0.57) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL25347680 | 0.79 | LMNA (0.52) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL28467166 | 0.79 | LMNA (0.52) | RXFP1LMNACYP1A2CYP2C9CYP2C19 | |
| Acetic Acid SCHEMBL28343497 | 0.78 | LMNA (0.54) | RXFP1LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091095-A | DIALKYLPHOSPHINYL-ALKYL ESTER OF A 2-(ARYL-AMINO) BENZOIC ACID, ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-05-23 | — | — | US | disclosed |