Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 9/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839649 | 0.87 | KDM4E (0.54) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2397058 | 0.86 | KDM4E (0.53) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11437705 | 0.86 | PRKCI (0.62) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5265936 | 0.85 | NAMPT (0.66) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9059907 | 0.85 | NAMPT (0.66) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21774243 | 0.84 | QPCT (0.63) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24819770 | 0.84 | QPCT (0.56) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30050799 | 0.82 | QPCT (0.75) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30212912 | 0.81 | QPCT (0.56) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24028037 | 0.81 | QPCT (0.56) | QPCTNAMPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105656-A | PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-08 | — | — | US | claimed |
| EP-2978425-B1 | FACTOR XIA INHIBITORS | MERCK SHARP & DOHME (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20160046581-A1 | Factor XIa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-02-18 | — | — | US | disclosed |
| US-4105656-A | PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046581-A1 | Factor XIa Inhibitors | F11, F12, TFPI | QPCT 2188/4885NAMPT 2823/4885RAB9A 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.