Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 9/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24028037 | 1.00 | QPCT (0.56) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL11580425 | 0.81 | QPCT (0.63) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL24819770 | 0.80 | QPCT (0.56) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL5265936 | 0.76 | NAMPT (0.66) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL9059907 | 0.76 | NAMPT (0.66) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL21774243 | 0.75 | QPCT (0.63) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL30050799 | 0.73 | QPCT (0.75) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL12082836 | 0.71 | RAB9A (0.73) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL24821503 | 0.70 | QPCT (0.60) | QPCTPOLBNAMPTP2RY14RAB9A | |
| SCHEMBL30050990 | 0.70 | QPCT (0.60) | QPCTPOLBNAMPTP2RY14RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149928-A1 | IMIDAZOLE 3-OXIDE DERIVATIVE BASED ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2023-03-22 | — | — | EP | disclosed |
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |