Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.70 |
| ▸ | DRD3 | P35462 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | GHSR | Q92847 | 2/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | HTR3A | P46098 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11579759 | 0.94 | OPRK1 (0.72) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11578252 | 0.91 | OPRK1 (0.72) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11581617 | 0.90 | TP53 (0.63) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11580136 | 0.89 | TP53 (0.56) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11579969 | 0.88 | OPRK1 (0.69) | OPRK1DRD3KCNH2GHSRHTR1A | |
| Elfazepam SCHEMBL259108 | 0.87 | OPRK1 (0.74) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11578526 | 0.87 | OPRK1 (0.64) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11578262 | 0.86 | OPRK1 (0.61) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11750221 | 0.86 | OPRK1 (0.69) | OPRK1DRD3KCNH2GHSRHTR1A | |
| SCHEMBL11745535 | 0.86 | OPRK1 (0.72) | OPRK1DRD3KCNH2GHSRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079053-A | Benzodiazepine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-03-14 | — | — | US | disclosed |
| US-4010154-A | Benzodiazepinones | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-01 | — | — | US | disclosed |
| US-3932637-A | 1-ALKYLSULFONYLALKYL-1,4-BENZODIAZEPINONES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-13 | — | — | US | disclosed |