Elfazepam

Elfazepam

SCHEMBL259108

CCS(=O)(=O)CCN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 5/20 0.74
DRD3 P35462 2/20 0.74
KCNH2 Q12809 2/20 0.74
GHSR Q92847 2/20 0.74
HTR1A P08908 1/20 0.74
HTR3A P46098 1/20 0.74
TP53 P04637 5/20 0.58
CYP3A4 P08684 2/20 0.52
SLC22A1 O15245 1/20 0.52
ABCB11 O95342 1/20 0.52
PDE4D Q08499 1/20 0.52
NR1I2 O75469 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
OPRM1 P35372 1/20 0.51
LMNA P02545 3/20 0.51
GABRA1 P14867 4/20 0.48
GABRA5 P31644 4/20 0.48
GABRA3 P34903 4/20 0.48
GABRA2 P47869 4/20 0.48
GABRB2 P47870 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11745535 0.94 OPRK1 (0.72) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11578252 0.94 OPRK1 (0.72) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11579759 0.91 OPRK1 (0.72) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11578948 0.90 OPRK1 (0.71) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11577333 0.90 TP53 (0.64) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11576688 0.89 OPRK1 (0.59) OPRK1DRD3KCNH2GHSRHTR1A
Elfazepam SCHEMBL1003682 0.89 OPRK1 (0.60) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11750221 0.89 OPRK1 (0.69) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11580468 0.87 OPRK1 (0.70) OPRK1DRD3KCNH2GHSRHTR1A
SCHEMBL11578284 0.87 OPRK1 (0.67) OPRK1DRD3KCNH2GHSRHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109006609-A A kind of high-quality three-dimensional interaction breeding method of cray ecology 黎建波 2018-12-18 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-4010154-A Benzodiazepinones SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-01 US claimed
US-3932637-A 1-ALKYLSULFONYLALKYL-1,4-BENZODIAZEPINONES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-01-13 US claimed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 US disclosed
US-12528794-B2 MAO-B inhibitor DRG-MAOB-1 for use in treatment of neurodegenerative diseases BAHCESEHIR UNIVERSITESI (TR) 2026-01-20 US disclosed
US-12478613-B2 Selective MAO-B inhibitor DRG-MAOB-2 for use in treatment of neurodegenerative diseases BAHCESEHIR UNIVERSITESI (TR) 2025-11-25 US disclosed
US-20250281535-A1 ANTI-HUMAN CD45RC BINDING DOMAINS AND USES THEREOF ABOLERIS PHARMA (FR) 2025-09-11 US disclosed
US-4675174-A Veterinary dispenser delivering beneficial agent by gas power generated in situ ALZA CORPORATION (US) 1987-06-23 US disclosed
US-4624945-A Dispensing system with means for increasing delivery of beneficial agent from the system ALZA CORPORATION (US) 1986-11-25 US disclosed
US-4612186-A Method for establishing blood levels of biocide in animals ALZA CORPORATION (US) 1986-09-16 US disclosed
US-4251506-A Controlled-release compositions for administration of therapeutic agents to ruminants COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1981-02-17 US disclosed
US-4079053-A Benzodiazepine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-14 US disclosed
US-4010154-A Benzodiazepinones SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 OPRK1 3689/4885DRD3 2949/4885KCNH2 2347/4885
US-12528794-B2 MAO-B inhibitor DRG-MAOB-1 for use in treatment of neurodegenerative diseases MAOB, MAOA, ME3 OPRK1 13/4885DRD3 1215/4885KCNH2 3831/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 OPRK1 3285/4885DRD3 2318/4885KCNH2 1946/4885
US-12478613-B2 Selective MAO-B inhibitor DRG-MAOB-2 for use in treatment of neurodegenerative diseases MAOB, MAOA, HTR2B OPRK1 7/4885DRD3 691/4885KCNH2 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.