Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135370 | 0.98 | THRB (0.49) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL3841280 | 0.84 | THRB (0.56) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL29413361 | 0.84 | THRB (0.56) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL30007447 | 0.79 | THRB (0.51) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL10871851 | 0.79 | THRB (0.51) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL14173222 | 0.79 | THRB (0.51) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL29497650 | 0.77 | THRB (0.50) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL7170318 | 0.77 | THRB (0.50) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL218920 | 0.77 | THRB (0.50) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL5887392 | 0.76 | MAPT (0.56) | THRBTHRAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888417-B2 | core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core | ACUSHNET COMPANY (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080261722-A1 | COMPOSITIONS FOR USE IN GOLF BALLS | ACUSHNET COMPANY | 2008-10-23 | — | — | US | disclosed |
| US-20080227567-A1 | COMPOSITIONS FOR USE IN GOLF BALLS | ACUSHNET COMPANY | 2008-09-18 | — | — | US | disclosed |
| US-20080176678-A1 | Compositions for Use in Golf Balls | ACUSHNET COMPANY | 2008-07-24 | — | — | US | disclosed |
| US-7361711-B2 | Compositions for use in golf balls | ACUSHNET COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7358309-B2 | core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core | ACUSHNET COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358310-B2 | Compositions for use in golf balls | ACUSHNET COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358308-B2 | Compositions for use in golf balls | ACUSHNET COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060281586-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | disclosed |
| US-20060281587-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-12-14 | — | — | US | disclosed |
| US-20050245652-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-11-03 | — | — | US | disclosed |
| US-20050245657-A1 | Compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-11-03 | — | — | US | disclosed |