Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686365 | 0.80 | ACHE (0.61) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL8048944 | 0.75 | ACHE (0.39) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL15467802 | 0.75 | ACHE (0.55) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL9543515 | 0.75 | ACHE (0.55) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL28911421 | 0.72 | ACHE (0.52) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL14224220 | 0.72 | ACHE (0.60) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL10522933 | 0.70 | ACHE (0.53) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL12863492 | 0.70 | ACHE (0.50) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL10530254 | 0.70 | ACHE (0.50) | ACHETDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL29030325 | 0.69 | ALDH1A3 (0.36) | KMT2AALDH1A1POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101323-A | Radiation-sensitive copying composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |