Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11579433 | 0.84 | BCAT2 (0.35) | PRNPNPSR1RXFP1NOTUMCSNK2A2 | |
| SCHEMBL11579764 | 0.84 | NOTUM (0.46) | PRNPNPSR1RXFP1NOTUMALDH1A1 | |
| SCHEMBL11578788 | 0.84 | NOTUM (0.46) | PRNPNPSR1RXFP1NOTUMALDH1A1 | |
| SCHEMBL11578914 | 0.82 | NOTUM (0.49) | PRNPNPSR1RXFP1NOTUMCSNK2A2 | |
| SCHEMBL11581714 | 0.81 | KDM4E (0.48) | PRNPALDH1A1LMNA | |
| SCHEMBL11554443 | 0.80 | CSNK2A2 (0.54) | PRNPNPSR1RXFP1CSNK2A2CSNK2B | |
| SCHEMBL1898735 | 0.74 | GABRP (0.40) | ALDH1A1LIMK1L3MBTL1LMNA | |
| SCHEMBL11580716 | 0.73 | MCL1 (0.47) | NOTUMALDH1A1 | |
| SCHEMBL7519571 | 0.73 | LIMK1 (0.49) | NPSR1ALDH1A1LIMK1L3MBTL1 | |
| SCHEMBL6749806 | 0.72 | KDM4E (0.41) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |