Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580707 | 0.83 | LMNA (0.38) | LMNAALDH1A1TSHRHSD17B10KCNH2 | |
| SCHEMBL11557666 | 0.83 | LMNA (0.38) | LMNAKCNH2 | |
| SCHEMBL11582014 | 0.83 | DAO (0.42) | LMNAKMT2AKCNH2 | |
| SCHEMBL11578367 | 0.81 | LMNA (0.43) | LMNAALDH1A1MAPK1TSHRHSD17B10 | |
| SCHEMBL11273643 | 0.81 | LMNA (0.51) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL11579951 | 0.79 | CNR2 (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL9835125 | 0.75 | HSD17B10 (0.43) | LMNAALDH1A1MAPK1TSHRGFER | |
| SCHEMBL11580726 | 0.73 | KMT2A (0.42) | LMNAALDH1A1MAPK1TSHRHSD17B10 | |
| SCHEMBL7479214 | 0.73 | KCNH2 (0.65) | LMNAKCNH2 | |
| SCHEMBL399326 | 0.70 | LMNA (0.56) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | claimed |
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3997545-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-12-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |