Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580735 | 0.83 | LMNA (0.38) | LMNAKCNH2ALDH1A1HSD17B10TSHR | |
| SCHEMBL11580748 | 0.82 | KDM4E (0.41) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11582014 | 0.82 | DAO (0.42) | LMNAKCNH2 | |
| SCHEMBL11557666 | 0.82 | LMNA (0.38) | LMNAKCNH2 | |
| SCHEMBL7470766 | 0.81 | KDM4E (0.48) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11821334 | 0.81 | BAZ2B (0.48) | LMNAMAP2K2MAP2K1KDM4EALDH1A1 | |
| SCHEMBL11580726 | 0.72 | KMT2A (0.42) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7479214 | 0.72 | KCNH2 (0.65) | LMNAKCNH2KDM4E | |
| SCHEMBL11580839 | 0.72 | KDM4E (0.38) | LMNAMAP2K2MAP2K1KDM4EALDH1A1 | |
| SCHEMBL4149665 | 0.70 | LMNA (0.54) | LMNAMAP2K2MAP2K1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |