Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945670 | 0.91 | HTR7 (0.50) | MAPTHSD17B10HPGDSMN1; SMN2HTR7 | |
| SCHEMBL942945 | 0.81 | HTR7 (0.42) | MAPTHSD17B10HPGDSMN1; SMN2HTR7 | |
| SCHEMBL943905 | 0.81 | HTR7 (0.42) | MAPTHSD17B10HPGDSMN1; SMN2HTR7 | |
| SCHEMBL6550775 | 0.79 | MAPT (0.52) | MAPTHSD17B10HPGDSMN1; SMN2MGLL | |
| SCHEMBL11574240 | 0.77 | HTR7 (0.44) | MAPTHSD17B10HPGDSMN1; SMN2MGLL | |
| Hydrogen Sulfide SCHEMBL27169707 | 0.77 | MAPT (0.50) | MAPTHSD17B10HPGDSMN1; SMN2MGLL | |
| Biphenyl SCHEMBL9957344 | 0.77 | HSD17B10 (0.80) | MAPTHSD17B10HPGDSMN1; SMN2MGLL | |
| SCHEMBL28967314 | 0.77 | HPGD (0.48) | MAPTHSD17B10HPGDSMN1; SMN2MGLL | |
| SCHEMBL8810988 | 0.76 | HTR7 (0.47) | MAPTHSD17B10HPGDSMN1; SMN2HTR7 | |
| SCHEMBL7737500 | 0.76 | MAPK1 (0.48) | MAPTHSD17B10HPGDHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082808-A | ANTIOXIDANTS, INTERMEDIATES FOR POLYESTERS, POLYCARBONATES, EPOXY RESINS | GENERAL ELECTRIC COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-3953519-A | BASES, EPOXY COMPOUNDS, OLEFINS | GENERAL ELECTRIC COMPANY (US) | 1976-04-27 | — | — | US | disclosed |