Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580664 | 0.92 | ADORA2A (0.45) | ADORA2ACYP1A1CYP1A2KDM4EMAPK1 | |
| SCHEMBL11580575 | 0.85 | ADORA2A (0.45) | ADORA2ACYP1A1CYP1A2KDM4EMAPK1 | |
| SCHEMBL11580476 | 0.85 | ADORA2A (0.45) | ADORA2ACYP1A1CYP1A2KDM4EMAPK1 | |
| SCHEMBL11580514 | 0.79 | ADORA2A (0.47) | ADORA2ACYP1A1CYP1A2KDM4EMAPK1 | |
| SCHEMBL11583208 | 0.75 | KDM4E (0.55) | ADORA2ACYP1A2KDM4EMAPK1MAPT | |
| SCHEMBL11580274 | 0.75 | MAPT (0.55) | ADORA2AKDM4EMAPK1MAPTNSD2 | |
| SCHEMBL6366580 | 0.74 | ADORA2A (0.58) | ADORA2ACYP1A2KDM4EMAPK1MAPT | |
| SCHEMBL11579534 | 0.73 | MAPT (0.75) | ADORA2AKDM4EMAPK1MAPTNSD2 | |
| SCHEMBL5585492 | 0.72 | ADORA2A (0.70) | ADORA2ACYP1A1CYP1A2MAPK1MAPT | |
| SCHEMBL11580527 | 0.71 | ADORA2A (0.56) | ADORA2AKDM4EMAPK1MAPTNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126626-A | DYES, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |