SCHEMBL1158249

SCHEMBL1158249

O=C(N[C@@H](CSC(=O)OCc1ccccc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.61
PPARG P37231 1/20 0.61
CTSK P43235 5/20 0.54
TACR1 P25103 2/20 0.51
FOLH1 Q04609 1/20 0.51
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51
CTRB1 P17538 2/20 0.50
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
CTSS P25774 1/20 0.50
CASP1 P29466 1/20 0.50
IDO1 P14902 1/20 0.50
TDO2 P48775 1/20 0.50
ITGB3 P05106 3/20 0.49
ITGA2B P08514 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8494629 1.00 PPARA (0.61) PPARAPPARGCTSKTACR1FOLH1
SCHEMBL16700660 0.88 PAM (0.51) PPARAPPARGCTSKTACR1FOLH1
SCHEMBL6890973 0.88 PPARA (0.60) PPARAPPARGCTSKTACR1CTSL
SCHEMBL21554078 0.88 PAM (0.51) PPARAPPARGCTSKTACR1FOLH1
SCHEMBL23927277 0.87 PPARA (0.73) PPARAPPARGCTSKTACR1CTRB1
SCHEMBL2748240 0.87 PPARA (0.65) PPARAPPARGCTSKTACR1CTRB1
SCHEMBL6835795 0.87 PPARA (0.65) PPARAPPARGCTSKTACR1CTRB1
SCHEMBL7354938 0.87 PPARA (0.65) PPARAPPARGCTSKTACR1CTRB1
SCHEMBL6835796 0.87 PPARA (0.65) PPARAPPARGCTSKTACR1CTRB1
SCHEMBL7302339 0.86 PPARA (0.64) PPARAPPARGCTSKTACR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-7888417-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2011-02-15 US disclosed
US-20080261722-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-10-23 US disclosed
US-20080227567-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-09-18 US disclosed
US-20080176678-A1 Compositions for Use in Golf Balls ACUSHNET COMPANY 2008-07-24 US disclosed
US-20060166295-A1 Method for determination of likelihood of occurrence of preterm labor in pregnant females NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2006-07-27 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
EP-1540341-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES The University of Rochester Medical Center (US) 2005-06-15 EP disclosed
WO-2004003555-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) 2004-01-08 WO disclosed
US-5856310-A ANTITUMOR AGENTS UNIVERSITY OF PITTSBURGH (US) 1999-01-05 US disclosed
US-5602098-A ANTICANCER AGENT UNIVERSITY OF PITTSBURGH (US) 1997-02-11 US disclosed
EP-0533516-B1 Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them ADIR (FR) 1995-02-08 EP disclosed
US-5340809-A Antihypoxic, antiischemic agents ADIR ET COMPAGNIE (FR) 1994-08-23 US disclosed
EP-0533516-A2 Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1993-03-24 EP disclosed