Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.73 |
| ▸ | PPARG | P37231 | 2/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285732 | 0.93 | PPARA (0.84) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL27533323 | 0.93 | PPARA (0.84) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL8584085 | 0.93 | PPARA (0.68) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11185687 | 0.92 | PPARA (0.64) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL6835795 | 0.91 | PPARA (0.65) | PPARAPPARGCTSKTACR1CTRB1 | |
| SCHEMBL7354938 | 0.91 | PPARA (0.65) | PPARAPPARGCTSKTACR1CTRB1 | |
| SCHEMBL2748240 | 0.91 | PPARA (0.65) | PPARAPPARGCTSKTACR1CTRB1 | |
| SCHEMBL6835796 | 0.91 | PPARA (0.65) | PPARAPPARGCTSKTACR1CTRB1 | |
| SCHEMBL21957908 | 0.90 | PPARA (0.65) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL21957907 | 0.90 | PPARA (0.65) | PPARAPPARGHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139281-B1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | UNIV HEIDELBERG (DE) | 2024-05-08 | — | — | EP | disclosed |
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-05-18 | — | — | US | disclosed |
| EP-4139281-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214243-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2021-10-28 | — | — | WO | disclosed |
| EP-3901135-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | Universität Heidelberg (DE) | 2021-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151054-A1 | SULFUR EXTRUSION FROM DISULFIDES BY CARBENES | TST, CBS, CTH | PPARA 3827/4885PPARG 3850/4885HDAC3 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.