Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583248 | 0.86 | MAPK1 (0.48) | MAPTKDM4ETDP1HSD17B10ALOX15 | |
| SCHEMBL11583036 | 0.86 | ESR1 (0.46) | MAPTKDM4ETDP1CYP1A2CYP2C9 | |
| SCHEMBL8901165 | 0.85 | HSD17B10 (0.58) | MAPTKDM4ETDP1HSD17B10HPGD | |
| SCHEMBL11730266 | 0.84 | MAPT (0.65) | MAPTKDM4ETDP1HSD17B10HPGD | |
| Phthalic Acid SCHEMBL4279595 | 0.80 | ALOX15 (0.52) | HSD17B10ALOX15CYP2C9ALDH1A1TSHR | |
| SCHEMBL30842657 | 0.80 | ALOX15 (0.47) | TDP1HSD17B10ALOX15ALDH1A1TSHR | |
| SCHEMBL60211 | 0.80 | ALOX15 (0.47) | TDP1HSD17B10ALOX15ALDH1A1TSHR | |
| SCHEMBL9789469 | 0.80 | TSHR (0.44) | KDM4ETDP1HSD17B10HPGDALOX15 | |
| Ammonia Solution, Strong SCHEMBL8767667 | 0.79 | ALOX15 (0.46) | TDP1HSD17B10ALOX15ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL5169572 | 0.79 | ALOX15 (0.46) | TDP1HSD17B10ALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101551-A | WATER INSOLUBILITY, AFFINITY FOR POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |