Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583036 | 0.87 | ESR1 (0.46) | MAPK1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11583307 | 0.86 | MAPT (0.51) | ALOX15HSD17B10LMNACYP1A2CYP2C19 | |
| SCHEMBL12430328 | 0.78 | LMNA (0.57) | MAPK1ALOX15HSD17B10LMNACYP1A2 | |
| SCHEMBL11584035 | 0.77 | LMNA (0.47) | MAPK1ALOX15HSD17B10LMNACYP1A2 | |
| SCHEMBL11522628 | 0.77 | TSHR (0.53) | ALOX15HSD17B10LMNACYP1A2CYP2C19 | |
| SCHEMBL11583249 | 0.76 | POLB (0.44) | MAPK1ALOX15HSD17B10LMNACYP1A2 | |
| SCHEMBL60211 | 0.74 | ALOX15 (0.47) | ALOX15HSD17B10ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL30842657 | 0.74 | ALOX15 (0.47) | ALOX15HSD17B10ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9789469 | 0.74 | TSHR (0.44) | MAPK1ALOX15HSD17B10LMNACYP2C19 | |
| SCHEMBL8901165 | 0.73 | HSD17B10 (0.58) | ALOX15HSD17B10LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101551-A | WATER INSOLUBILITY, AFFINITY FOR POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |