Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | PTPRF | P10586 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 1/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.56 |
| ▸ | PRKCB | P05771 | 2/20 | 0.56 |
| ▸ | PRKCA | P17252 | 2/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | PRKACG | P22612 | 1/20 | 0.56 |
| ▸ | PRKACB | P22694 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951074 | 0.86 | PTPN1 (0.73) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL27750430 | 0.78 | PTPN11 (0.56) | PTPRCPTPRFPTPN1CDC25BPRKCB | |
| SCHEMBL27721368 | 0.78 | PTPN11 (0.56) | PTPN1NR4A2MEN1KMT2AALDH1A1 | |
| SCHEMBL21814328 | 0.78 | LMNA (0.44) | PTPRCPTPRFPTPN1CDC25BCCR6 | |
| SCHEMBL7737770 | 0.78 | PDGFRB (0.44) | PTPN1PRKD3CCNB2ABL1CDK1 | |
| SCHEMBL27771326 | 0.78 | PTPN1 (0.61) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL27795880 | 0.78 | PTPN1 (0.61) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL27771327 | 0.76 | PTPRC (0.56) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL27771325 | 0.76 | PTPRC (0.56) | PTPRCPTPRFPTPN1CDC25BSIRT2 | |
| SCHEMBL9572016 | 0.75 | PTPN1 (0.77) | PTPRCPTPRFPTPN1CDC25BSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471046-B | Carbazole indole quinone derivative and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-116924960-A | Method for synthesizing 3-indolyl benzoquinone compound | 郑州大学 | 2023-10-24 | — | — | CN | claimed |
| CN-113200967-B | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113200967-A | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2021-08-03 | — | — | CN | claimed |
| CN-112174872-A | Indole benzoquinone derivative as fluorescent and photoacoustic imaging agent and application thereof | 四川大学 | 2021-01-05 | — | — | CN | claimed |
| CN-110437124-A | A kind of indoles quinone derivative and preparation method thereof | CHENGDU ORGANIC CHEM CO LTD CAS | 2019-11-12 | — | — | CN | claimed |
| CN-105646490-B | The cyclohexadione compounds of indoles [1,2 a] pyrimidine [4,5 b] quinoline 7,13, preparation method and its medicinal usage | 西北大学 | 2018-01-09 | — | — | CN | claimed |
| US-20080227168-A1 | METHODS AND MATERIALS FOR EXTRA AND INTRACELLULAR DELIVERY OF CARBON NANOTUBES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-09-18 | — | — | US | claimed |
| EP-1900850-A1 | PHOTOELECTROCHEMICAL METHOD OF SEPARATING WATER INTO HYDROGEN AND OXYGEN, USING MELANINS OR THE ANALOGUES, PRECURSORS OR DERIVATIVES THEREOF AS THE CENTRAL ELECTROLYSING ELEMENT | Solis Herrera, Arturo (MX) | 2008-03-19 | — | — | EP | claimed |
| EP-0959881-B1 | SYNTHETIC METHODS FOR THE PREPARATION OF INDOLYLQUINONES AND MONO- AND BIS-INDOLYLQUINONES PREPARED THEREFROM | SUGEN INC (US) | 2005-09-21 | — | — | EP | claimed |
| US-20030060635-A1 | Methods of using bis-indolylquinones | TANG PENG C (US) | 2003-03-27 | — | — | US | claimed |
| EP-0959881-A4 | SYNTHETIC METHODS FOR THE PREPARATION OF INDOLYLQUINONES AND MONO- AND BIS-INDOLYLQUINONES PREPARED THEREFROM | SUGEN INC (US) | 2001-06-27 | — | — | EP | claimed |
| EP-0959881-A1 | SYNTHETIC METHODS FOR THE PREPARATION OF INDOLYLQUINONES AND MONO- AND BIS-INDOLYLQUINONES PREPARED THEREFROM | Sugen, Inc. (US) | 1999-12-01 | — | — | EP | claimed |
| US-5786488-A | DEHYDROBROMINATION OF A DIBROMOBENZOQUINONES WITH AT LEAST ONE INDOLES IN A POLAR SOLVENT AND A METAL CARBONATE TO FORM AN ANTITUMOR AGENT | SUGEN, INC. (US) | 1998-07-28 | — | — | US | claimed |
| WO-1998020874-A1 | SYNTHETIC METHODS FOR THE PREPARATION OF INDOLYLQUINONES AND MONO- AND BIS-INDOLYLQUINONES PREPARED THEREFROM | SUGEN, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| JP-57050959-A | — | — | None | — | — | JP | disclosed |
| JP-57050959-A | — | — | None | — | — | JP | disclosed |
| JP-S5750959-A | INDOLE QUINONE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1982-03-25 | — | — | JP | disclosed |
| JP-S5750959-A | INDOLE QUINONE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1982-03-25 | — | — | JP | disclosed |
| US-3987202-A | METHOD OF TREATING PSORIASIS | OKUN MILTON R | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060635-A1 | Methods of using bis-indolylquinones | IDO2, IDO1, IPO5 | PTPRC 3030/4885PTPRF 3523/4885PTPN1 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.