SCHEMBL11586019

SCHEMBL11586019

OC(c1ccccc1)(c1ccccc1F)C(O)(c1ccccc1)c1ccccc1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 8/20 0.53
KCNE1 P15382 1/20 0.47
KCNQ1 P51787 1/20 0.47
KIF11 P52732 2/20 0.40
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
TBXA2R P21731 1/20 0.38
CCKBR P32239 1/20 0.38
OPRK1 P41145 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
NR3C1 P04150 1/20 0.37
PTPN1 P18031 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7025019 0.82 KCNN4 (0.42) KCNN4KCNE1KCNQ1KIF11CYP3A4
SCHEMBL11598635 0.82 KCNN4 (0.45) KCNN4KCNE1KCNQ1KIF11MLNR
SCHEMBL2243767 0.82 KCNN4 (0.53) KCNN4KCNE1KCNQ1KIF11CYP3A4
SCHEMBL5162272 0.80 KCNN4 (0.52) KCNN4KCNE1KCNQ1KIF11ALDH1A1
SCHEMBL11597752 0.79 KCNN4 (0.58) KCNN4KCNE1KCNQ1KIF11CYP3A4
SCHEMBL18674881 0.79 KCNN4 (0.41) KCNN4KCNE1KCNQ1KIF11ALDH1A1
SCHEMBL7768876 0.77 ALDH1A1 (0.50) KCNN4KIF11CYP3A4MAPK1ALDH1A1
SCHEMBL20263102 0.77 KCNN4 (0.40) KCNN4KCNE1KCNQ1CYP3A4MAPK1
SCHEMBL1443904 0.75 KCNN4 (0.58) KCNN4KCNE1KCNQ1CYP3A4MLNR
SCHEMBL28905887 0.75 KCNN4 (0.56) KCNN4KCNE1KCNQ1KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4106938-A VESICULATING AGENT WHICH LIBERATES GAS ON EXPOSURE TO ACTIVATING RADIATION, THERMOPLASTIC BINDER, DIOL SPEED-INCREASING AGENT EASTMAN KODAK COMPANY (US) 1978-08-15 US claimed
US-11926727-B2 Epoxy resin composition HUNTSMAN INTERNATIONAL LLC (US) 2024-03-12 US disclosed
US-20220135766-A1 Epoxy Resin Composition HUNTSMAN INTERNATIONAL LLC 2022-05-05 US disclosed
EP-3310838-B1 EPOXY RESIN COMPOSITION HUNTSMAN ADV MAT LICENSING SWITZERLAND GMBH (CH) 2021-08-18 EP disclosed
US-20180171101-A1 Epoxy Resin Composition HUNTSMAN INTERNATIONAL LLC 2018-06-21 US disclosed
US-4106938-A VESICULATING AGENT WHICH LIBERATES GAS ON EXPOSURE TO ACTIVATING RADIATION, THERMOPLASTIC BINDER, DIOL SPEED-INCREASING AGENT EASTMAN KODAK COMPANY (US) 1978-08-15 US disclosed