Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | SPOP | O43791 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586499 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL9876995 | 0.87 | HSD17B10 (0.48) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL9876998 | 0.87 | HSD17B10 (0.48) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL9366596 | 0.87 | TDP1 (0.75) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL9366601 | 0.87 | TDP1 (0.75) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL11090140 | 0.86 | ALDH1A1 (0.59) | TDP1MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL11090143 | 0.86 | ALDH1A1 (0.59) | TDP1MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL11585209 | 0.86 | ALDH1A1 (0.59) | TDP1MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL11585206 | 0.86 | ALDH1A1 (0.59) | TDP1MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL4606522 | 0.86 | MAPT (0.59) | TDP1MAPTPOLBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110534-A | PROCESS FOR THE PREPARATION OF 3-VINYL AND SUBSTITUTED VINYL CEPHALOSPORINS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4107431-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |