Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876998 | 1.00 | HSD17B10 (0.48) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11090140 | 0.89 | ALDH1A1 (0.59) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11090143 | 0.89 | ALDH1A1 (0.59) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11585209 | 0.89 | ALDH1A1 (0.59) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11585206 | 0.89 | ALDH1A1 (0.59) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11577111 | 0.88 | ALDH1A1 (0.52) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11577116 | 0.88 | ALDH1A1 (0.52) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL7806298 | 0.87 | PTGS1 (0.49) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11586495 | 0.87 | TDP1 (0.55) | HSD17B10ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL11586499 | 0.87 | TDP1 (0.55) | HSD17B10ALDH1A1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985555-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4871730-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0268307-A2 | New starting compounds for cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | disclosed |
| EP-0133678-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4271305-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4226986-A | 7-ACYLAMINO-3-HYDROXY-3-CEPHEM COMPOUND, TRIARYL PHOSPHITE DIHALIDE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |