Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518495 | 0.87 | PDE4D (0.43) | PDE4DMAPTGAAKMT2ARXFP1 | |
| SCHEMBL5957802 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1PHLPP2MAPTGAA | |
| SCHEMBL4649630 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1PHLPP2MAPTGAA | |
| SCHEMBL11587276 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1PHLPP2MAPTGAA | |
| SCHEMBL23144411 | 0.74 | KMT2A (0.54) | PDE4DMAPTKMT2ARXFP1SIGMAR1 | |
| SCHEMBL29811288 | 0.74 | KMT2A (0.54) | PDE4DMAPTKMT2ARXFP1SIGMAR1 | |
| SCHEMBL11522008 | 0.73 | CYP2D6 (0.49) | GAAKMT2ARXFP1SIGMAR1ALDH1A1 | |
| SCHEMBL13152007 | 0.73 | PTGS2 (0.51) | PTGS2PTGS1PHLPP2MAPTGAA | |
| SCHEMBL11517824 | 0.72 | CA12 (0.47) | GAAKMT2ARXFP1ALDH1A1 | |
| SCHEMBL5720651 | 0.71 | ALDH1A1 (0.59) | PTGS2PTGS1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118381-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |