Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667190 | 0.91 | MAPK1 (0.56) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11593599 | 0.91 | EPAS1 (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11591036 | 0.91 | POLB (0.48) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11592911 | 0.90 | MEN1 (0.43) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11589108 | 0.90 | L3MBTL1 (0.51) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11594761 | 0.90 | MAPK1 (0.52) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11587958 | 0.90 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11592857 | 0.90 | POLB (0.47) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11593993 | 0.90 | ALDH1A1 (0.45) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11592989 | 0.88 | ALDH1A1 (0.51) | MEN1KMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |
| US-4084004-A | Rodenticidal use of diphenylamines | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |