SCHEMBL11587787

SCHEMBL11587787

N#Cc1ccccc1N=Cc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.75
ALDH1A1 P00352 5/20 0.55
SMN1; SMN2 Q16637 4/20 0.50
MAPT P10636 5/20 0.46
KDM4E B2RXH2 4/20 0.46
HPGD P15428 4/20 0.46
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
POLB P06746 2/20 0.42
USP2 O75604 1/20 0.42
CASP1 P29466 1/20 0.42
BRCA1 P38398 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
DHODH Q02127 1/20 0.41
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
CHAT P28329 1/20 0.39
GAA P10253 2/20 0.39
RAB9A P51151 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11796171 1.00 LMNA (0.75) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL16620673 0.86 LMNA (0.71) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL16620671 0.86 LMNA (0.71) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL16620590 0.83 LMNA (0.59) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL16620588 0.83 LMNA (0.59) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL8619952 0.82 LMNA (0.66) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL10410006 0.82 LMNA (0.66) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL10410005 0.82 LMNA (0.66) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL7919925 0.81 LMNA (0.51) LMNAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL7378146 0.80 LMNA (0.51) LMNAALDH1A1SMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US claimed
EP-3052531-B1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORP (JP) 2024-07-24 EP disclosed
US-11066486-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2021-07-20 US disclosed
US-20200157253-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2020-05-21 US disclosed
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US disclosed
CN-107406770-A Metallomesogen dyestuff 哥兹有限公司 2017-11-28 CN disclosed
CN-105814087-B Polymers functionalized with imine compounds containing cyano groups 株式会社普利司通 2017-07-11 CN disclosed
US-20160237179-A1 Polymers Functionalized With Imine Compounds Containing A Cyano Group BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed
EP-3052531-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2016-08-10 EP disclosed
WO-2015050947-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-04-09 WO disclosed
EP-0001655-A2 Compositions comprising as active ingredients cyanobenzyl(idene)-aniline derivatives, the use of the compositions as plant growth regulants and a method for the preparation of the active ingredients SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-05-02 EP disclosed
US-3981558-A Liquid crystal electro-optical display TIMEX CORPORATION (US) 1976-09-21 US disclosed
US-3981558-A Liquid crystal electro-optical display TIMEX CORPORATION (US) 1976-09-21 US disclosed
US-3927064-A Benzylidene-aminobenzonitriles HOFFMANN LA ROCHE (CH) 1975-12-16 US disclosed