Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 10/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747518 | 0.94 | SOAT1 (0.45) | SOAT1PTGS2KDM4EALDH1A1GAA | |
| SCHEMBL2426921 | 0.94 | SOAT1 (0.45) | SOAT1PTGS2KDM4EALDH1A1GAA | |
| SCHEMBL10335607 | 0.91 | ALDH1A1 (0.42) | SOAT1PTGS2KDM4EALDH1A1GAA | |
| Formamide SCHEMBL28145518 | 0.88 | SOAT1 (0.40) | SOAT1PTGS2KDM4EALDH1A1GAA | |
| SCHEMBL21111964 | 0.84 | KDM4E (0.44) | SOAT1S100A4KDM4EALDH1A1GAA | |
| SCHEMBL30609814 | 0.81 | KDM4E (0.45) | S100A4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL11604127 | 0.81 | GSK3B (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9017718 | 0.80 | SOAT1 (0.49) | SOAT1PTGS2S100A4KDM4EP4HB | |
| SCHEMBL2359302 | 0.78 | GSK3B (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10581743 | 0.77 | SOAT1 (0.54) | SOAT1PTGS2S100A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4068071-A | DISULFIDING, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |
| CN-108350018-A | The manufacturing method of oligonucleotides | 日产化学工业株式会社 | 2018-07-31 | — | — | CN | disclosed |
| US-4068071-A | DISULFIDING, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | disclosed |