Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 9/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747518 | 1.00 | SOAT1 (0.45) | SOAT1PTGS2P4HBGAASMN1; SMN2 | |
| SCHEMBL11588296 | 0.94 | SOAT1 (0.42) | SOAT1PTGS2P4HBGAASMN1; SMN2 | |
| Formamide SCHEMBL28145518 | 0.94 | SOAT1 (0.40) | SOAT1PTGS2P4HBGAASMN1; SMN2 | |
| SCHEMBL10335607 | 0.88 | ALDH1A1 (0.42) | SOAT1PTGS2P4HBGAAMEN1 | |
| SCHEMBL7855715 | 0.82 | SOAT1 (0.52) | SOAT1PTGS2P4HBCYSLTR2CYSLTR1 | |
| SCHEMBL21111964 | 0.82 | KDM4E (0.44) | SOAT1GAAMEN1MAPTKMT2A | |
| SCHEMBL30609814 | 0.79 | KDM4E (0.45) | GAASMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL11604127 | 0.79 | GSK3B (0.39) | GAAMEN1MAPTKMT2AKDM4E | |
| SCHEMBL23388947 | 0.78 | SOAT1 (0.56) | SOAT1PTGS2P4HBMEN1MAPT | |
| SCHEMBL29886439 | 0.78 | SOAT1 (0.56) | SOAT1PTGS2P4HBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697447-B2 | Cleavable surfactants and methods of use thereof | VANDERBILT UNIVERSITY (US) | 2014-04-15 | — | — | US | disclosed |
| US-20110217783-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY | 2011-09-08 | — | — | US | disclosed |
| EP-1404643-A4 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | UNIV VANDERBILT (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20060240562-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | CAPRIOLI RICHARD M | 2006-10-26 | — | — | US | disclosed |
| US-7074936-B2 | Cleavable surfactants and methods of use thereof | VANDERBILT UNIVERSITY (US) | 2006-07-11 | — | — | US | disclosed |
| US-20040152913-A1 | Cleavable surfactants and methods of use thereof | VANDERBILT UNIVERSITY | 2004-08-05 | — | — | US | disclosed |
| EP-1404643-A2 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002097393-A2 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110217783-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | PHOSPHO1, SGMS1, SGMS2 | SOAT1 2659/4885PTGS2 4150/4885P4HB 760/4885 |
| US-20060240562-A1 | CLEAVABLE SURFACTANTS AND METHODS OF USE THEREOF | ADAM33, ADAM17, TMPRSS15 | SOAT1 3464/4885PTGS2 4110/4885P4HB 267/4885 |
| US-20040152913-A1 | Cleavable surfactants and methods of use thereof | ADAM33, ADAM17, TMPRSS15 | SOAT1 3464/4885PTGS2 4110/4885P4HB 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.