Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152165 | 0.88 | MERTK (0.58) | MERTKMEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL10797141 | 0.88 | MERTK (0.48) | MERTKMEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL11593456 | 0.87 | MEN1 (0.51) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11593772 | 0.87 | MAPT (0.48) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11589949 | 0.86 | VCAM1 (0.47) | MERTKMEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL11137496 | 0.85 | MEN1 (0.49) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11587736 | 0.85 | MAPK1 (0.49) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11588380 | 0.84 | KMT2A (0.42) | MERTKMEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL11591052 | 0.84 | MAPT (0.40) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL10527347 | 0.84 | MAPT (0.56) | MEN1KMT2AHSP90AA1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |
| US-4084004-A | Rodenticidal use of diphenylamines | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |