SCHEMBL11588746

SCHEMBL11588746

Cc1ccc(N=Cc2ccc(C=Nc3ccc(C)cc3)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.74
CA2 P00918 4/20 0.67
PTGS2 P35354 3/20 0.67
CA9 Q16790 2/20 0.67
PTGS1 P23219 1/20 0.67
CA12 O43570 1/20 0.67
SMN1; SMN2 Q16637 4/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
KDM4E B2RXH2 4/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
MAPT P10636 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
TP53 P04637 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12633723 1.00 ALDH1A1 (0.74) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL20186922 1.00 ALDH1A1 (0.74) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL255410 1.00 ALDH1A1 (0.74) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL11557679 1.00 ALDH1A1 (0.74) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL28162394 0.91 ALDH1A1 (0.65) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL14129141 0.91 ALDH1A1 (0.65) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL13351563 0.89 ALDH1A1 (0.62) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL18688365 0.89 ALDH1A1 (0.62) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL11458614 0.89 S100B (0.66) ALDH1A1CA2PTGS2CA9PTGS1
SCHEMBL22366969 0.89 ALDH1A1 (0.62) ALDH1A1CA2PTGS2CA9PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210187902-A1 LAMINATE, ELECTRONIC DEVICE, AND PRODUCTION METHOD FOR LAMINATE JNC CORPORATION (JP) 2021-06-24 US disclosed
US-20210101373-A1 LAMINATE, ELECTRONIC EQUIPMENT AND PRODUCTION METHOD FOR LAMINATE JNC CORPORATION (JP) 2021-04-08 US disclosed
US-20190055444-A1 COMPOSITION FOR LOW THERMAL EXPANSION MEMBERS, LOW THERMAL EXPANSION MEMBER, ELECTRONIC DEVICE, AND METHOD FOR PRODUCING LOW THERMAL EXPANSION MEMBER JNC CORPORATION (JP) 2019-02-21 US disclosed
EP-2799516-B1 LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF HALATION PHOTONICS CORP (CN) 2019-02-20 EP disclosed
US-10202530-B2 Composition for heat-dissipation members, heat-dissipation member, electronic device, and method of producing heat dissipating member JNC CORPORATION (JP) 2019-02-12 US disclosed
US-9938371-B2 Composition for heat-dissipation member, heat-dissipation member, and electronic device JNC CORPORATION (JP) 2018-04-10 US disclosed
US-9938371-B2 Composition for heat-dissipation member, heat-dissipation member, and electronic device JNC CORPORATION (JP) 2018-04-10 US disclosed
US-20170306207-A1 COMPOSITION FOR HEAT-DISSIPATION MEMBERS, HEAT-DISSIPATION MEMBER, ELECTRONIC DEVICE, AND HEAT-DISSIPATION-MEMBER PRODUCTION METHOD JNC CORPORATION (JP) 2017-10-26 US disclosed
US-20170306207-A1 COMPOSITION FOR HEAT-DISSIPATION MEMBERS, HEAT-DISSIPATION MEMBER, ELECTRONIC DEVICE, AND HEAT-DISSIPATION-MEMBER PRODUCTION METHOD JNC CORPORATION (JP) 2017-10-26 US disclosed
US-20170137561-A1 COMPOSITION FOR HEAT-DISSIPATION MEMBERS, HEAT-DISSIPATION MEMBER, AND ELECTRONIC DEVICE JNC CORPORATION (JP) 2017-05-18 US disclosed
US-20170137561-A1 COMPOSITION FOR HEAT-DISSIPATION MEMBERS, HEAT-DISSIPATION MEMBER, AND ELECTRONIC DEVICE JNC CORPORATION (JP) 2017-05-18 US disclosed
EP-3141589-A1 COMPOSITION FOR HEAT-DISSIPATION MEMBERS, HEAT-DISSIPATION MEMBER, AND ELECTRONIC DEVICE JNC Corporation (JP) 2017-03-15 EP disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-4073767-A Hydrogen phosphonates and polymers containing them as flame retardants MONSANTO COMPANY (US) 1978-02-14 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed