SCHEMBL11588985

SCHEMBL11588985

C=C(CCC(O)CN(O)CC)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2883814 0.84 L3MBTL1 (0.46) TET2TET3TET1L3MBTL1GRIK1
SCHEMBL8010424 0.80 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL154215 0.77 TET2 (0.40) TET2TET3TET1GRIK1GRIK2
SCHEMBL1353706 0.76 FFAR4 (0.41) TET2TET3TET1GRIK1GRIK2
SCHEMBL9577642 0.73 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL3392396 0.73 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL613228 0.73 FFAR4 (0.52)
SCHEMBL1074950 0.72 TET2 (0.46) TET2TET3TET1GRIK1GRIK2
SCHEMBL243507 0.71 TET2 (0.41) TET2TET3TET1GRIK1GRIK2
SCHEMBL23251 0.71 CA1 (0.48) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4128636-A Cosmetic emulsions containing copolymers of 2-hydroxy-3-hydroxyalkyl-aminopropyl(meth)acrylates and alkyl (meth)acrylates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-12-05 US disclosed