Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832216 | 0.87 | MEN1 (0.68) | SUCNR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16583930 | 0.86 | DHODH (0.73) | SUCNR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11594686 | 0.85 | NPC1 (0.63) | KMT2ANPC1RAB9AMEN1DHODH | |
| SCHEMBL6240737 | 0.84 | MEN1 (0.68) | SUCNR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11592326 | 0.81 | F10 (0.66) | KMT2ANPC1RAB9AMEN1PKM | |
| SCHEMBL6848585 | 0.80 | NPC1 (0.54) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL11594362 | 0.80 | CYP1A2 (0.68) | KMT2ANPC1RAB9AMEN1KDR | |
| SCHEMBL6847188 | 0.79 | NPC1 (0.53) | KMT2ANPC1RAB9AMEN1DHODH | |
| SCHEMBL2293960 | 0.78 | SERPINE1 (0.76) | SUCNR1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9767724 | 0.78 | KMT2A (0.79) | KMT2ANPC1RAB9AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088651-A | Acylamino quinophthalone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |