Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.59 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514283 | 0.87 | HPGD (0.77) | CYP1A2HPGDCYP2C19SLC16A3PBRM1 | |
| SCHEMBL6848585 | 0.85 | NPC1 (0.54) | PBRM1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL6847188 | 0.83 | NPC1 (0.53) | PBRM1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7832216 | 0.82 | MEN1 (0.68) | CYP1A2HPGDCYP2C19RAB9AMEN1 | |
| SCHEMBL8279069 | 0.81 | HPGD (0.68) | CYP1A2HPGDCYP2C19SLC16A3ALDH1A1 | |
| SCHEMBL11155741 | 0.81 | PBRM1 (0.58) | CYP1A2HPGDCYP2C19SLC16A3PBRM1 | |
| SCHEMBL6848512 | 0.80 | KMT2A (0.65) | CYP1A2HPGDPBRM1ALDH1A1RAB9A | |
| SCHEMBL2700280 | 0.80 | CYP1A2 (0.77) | CYP1A2HPGDCYP2C19SLC16A3PBRM1 | |
| SCHEMBL11590186 | 0.80 | SUCNR1 (0.58) | KDRPABPC1EIF4HRAB9AMEN1 | |
| SCHEMBL13690053 | 0.79 | HPGD (0.64) | CYP1A2HPGDCYP2C19SLC16A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088651-A | Acylamino quinophthalone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |