Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590885 | 1.00 | SNCA (0.44) | SNCAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL17356869 | 0.83 | SNCA (0.56) | SNCAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL11686903 | 0.81 | ALDH1A1 (0.41) | SNCAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL11686919 | 0.81 | ALDH1A1 (0.41) | SNCAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL30867068 | 0.79 | SNCA (0.53) | SNCAMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL29214101 | 0.79 | SNCA (0.53) | SNCAMAPTMEN1KMT2ACYP1A2 | |
| Iodide SCHEMBL10821222 | 0.75 | PRMT1 (0.70) | MAPTMEN1KMT2AUSP2NPC1 | |
| Hydrochloric Acid SCHEMBL11536389 | 0.75 | PRMT1 (0.67) | MAPTMEN1KMT2AUSP2NPC1 | |
| SCHEMBL11714460 | 0.74 | MAPT (0.58) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL11714457 | 0.74 | MAPT (0.58) | MAPTMEN1KMT2AUSP2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110116-A | Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4035190-A | 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
| US-4025347-A | Fogged direct-positive silver halide emulsion containing a cyanine dye having an indole or indolenine nucleus substituted with a benzoyl or a phenylsulfonyl group | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-4007170-A | SILVER HALIDE SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3936308-A | Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |