Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380374 | 0.95 | KCNT1 (0.59) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12530633 | 0.89 | KCNT1 (0.56) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12531030 | 0.88 | HSD17B10 (0.68) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26086379 | 0.87 | CA12 (0.62) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26086339 | 0.86 | KCNT1 (0.51) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21163949 | 0.81 | HSD17B10 (0.59) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5854479 | 0.79 | HTR2A (0.48) | SLC2A1CA12CA2CA9 | |
| SCHEMBL12305654 | 0.77 | HSD17B10 (0.69) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13219070 | 0.77 | HSD17B10 (0.63) | KCNT1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8398635 | 0.77 | HSD17B10 (0.68) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129556-A | N,N'-BIS-(2-HYDROXYBENZYL)-ALKYLENE-DIAMINES, N,N'-BIS-(2-HYDROXYBENZYL)-ARYLENE-DIAMINES | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |