Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 6/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380374 | 0.92 | KCNT1 (0.59) | KDM4EHSD17B10KCNT1CYP1A2CYP2C9 | |
| SCHEMBL11593078 | 0.87 | KCNT1 (0.60) | CA12CA2CA9KDM4EHSD17B10 | |
| SCHEMBL26087028 | 0.86 | CA12 (0.70) | CA12CA2CA9KDM4EHSD17B10 | |
| SCHEMBL26087538 | 0.85 | CA12 (0.64) | CA12CA2CA9KDM4EHSD17B10 | |
| SCHEMBL26086339 | 0.83 | KCNT1 (0.51) | KDM4EHSD17B10KCNT1CYP1A2CYP2C9 | |
| SCHEMBL26087471 | 0.82 | CA12 (0.92) | CA12CA2CA9KDM4EHSD17B10 | |
| SCHEMBL12530633 | 0.80 | KCNT1 (0.56) | KDM4EHSD17B10KCNT1CYP1A2CYP2C9 | |
| SCHEMBL12531030 | 0.79 | HSD17B10 (0.68) | KDM4EHSD17B10KCNT1CYP1A2CYP2C9 | |
| SCHEMBL11241212 | 0.79 | CA12 (1.00) | CA12CA2CA9KDM4EHSD17B10 | |
| SCHEMBL24435599 | 0.77 | CA12 (1.00) | CA12CA2CA9KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409496-A1 | SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2024-12-12 | — | — | US | disclosed |
| EP-4423055-A1 | SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES | Consejo Superior de Investigaciones Cientificas (ES) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023072434-A1 | SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2023-05-04 | — | — | WO | disclosed |
| EP-4169902-A1 | SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2023-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409496-A1 | SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES | SMS, SRM, SMOX | CA12 1596/4885CA2 2529/4885CA9 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.