Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.55 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531030 | 0.89 | HSD17B10 (0.68) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL12530633 | 0.84 | KCNT1 (0.56) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL12305654 | 0.82 | HSD17B10 (0.69) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL11593078 | 0.81 | KCNT1 (0.60) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL7129826 | 0.80 | HSD17B10 (0.66) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL30380374 | 0.80 | KCNT1 (0.59) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL3361843 | 0.80 | HSD17B10 (0.70) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL13219070 | 0.79 | HSD17B10 (0.63) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| 1-Naphthol SCHEMBL5077720 | 0.78 | CYP1A2 (0.68) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL7904045 | 0.78 | HTR2A (0.50) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738157-B1 | AUTO-MAGNETIC METAL SALEN COMPLEX COMPOUND | IHI CORP (JP) | 2019-07-10 | — | — | EP | disclosed |