Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | TIMP3 | P35625 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 6/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.59 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 4/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.59 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.59 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593406 | 0.89 | TIMP3 (0.55) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11593413 | 0.88 | TIMP3 (0.66) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11413358 | 0.87 | TIMP3 (0.52) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11426644 | 0.85 | TIMP3 (0.51) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11468629 | 0.84 | TIMP3 (0.53) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11407252 | 0.84 | TIMP3 (0.53) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11413353 | 0.81 | TIMP3 (0.59) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11512704 | 0.81 | KMT2A (0.57) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11465117 | 0.81 | TIMP3 (0.50) | RECQLKMT2AHSD17B10TDP1TIMP3 | |
| SCHEMBL11426011 | 0.80 | TIMP3 (0.77) | RECQLKMT2AHSD17B10TDP1TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108890-A | Nitro or amino phenylenebis(carbonylimino)dinaphthalenetrisulfonic compounds as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4051176-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-09-27 | — | — | US | disclosed |