Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | BCKDK | O14874 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 10/20 | 0.34 |
| ▸ | MMP13 | P45452 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809774 | 0.92 | CYP1A2 (0.47) | CYP1A2HRH4MAPTALDH1A1RAB9A | |
| SCHEMBL11244498 | 0.89 | BCL2L1 (0.44) | CYP1A2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL28458734 | 0.88 | KDM4E (0.46) | CYP1A2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL11041632 | 0.87 | CYP1A2 (0.60) | CYP1A2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL11236091 | 0.87 | ALDH1A1 (0.50) | CYP1A2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL11247121 | 0.84 | BCKDK (0.51) | CYP1A2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL28460242 | 0.83 | KDM4E (0.40) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28458672 | 0.83 | KDM4E (0.47) | CYP1A2HRH4MAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11595018 | 0.81 | CYP1A2 (0.50) | CYP1A2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL9329684 | 0.80 | KDM4E (0.53) | CYP1A2MAPTALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |