SCHEMBL11595271

SCHEMBL11595271

Cc1cc2c(cc1C)Sc1cc(Cl)c(Cl)cc1S2

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.35
CYP3A4 P08684 2/20 0.32
CHRM1 P11229 1/20 0.31
ALOX15 P16050 1/20 0.31
MAOA P21397 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
MAPK1 P28482 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507665 0.89 CD44 (0.46) CD44CYP3A4CHRM1ALOX15MAOA
SCHEMBL9508103 0.89 CD44 (0.46) CD44CYP3A4CHRM1ALOX15MAOA
SCHEMBL9510026 0.85 AHR (0.39) CYP3A4MAPK1AHR
SCHEMBL11427006 0.85 CYP3A4 (0.35) CYP3A4MAPK1
SCHEMBL9698315 0.76 PRKCE (0.31)
SCHEMBL172591 0.75 CD44 (0.45) CD44CYP3A4CHRM1ALOX15MAOA
SCHEMBL3422095 0.72 MAOA (0.42) CYP3A4CHRM1ALOX15MAOAADRA1A
SCHEMBL9508168 0.70 CYP2A6 (0.39) MAPK1
SCHEMBL10652247 0.69 AHR (0.44) CD44CYP3A4AHR
SCHEMBL811040 0.67 CD44 (0.39) CD44CYP3A4CHRM1ALOX15MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4069264-A CHLORINE, LEWIS ACID CATALYST, THIANTHRENE COMPOUND AS CO-CATALYST HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-01-17 US disclosed