Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595283 | 1.00 | CNR2 (0.54) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11527071 | 0.89 | ALDH1A1 (0.52) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11525232 | 0.88 | ALDH1A1 (0.53) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11349061 | 0.87 | ALDH1A1 (0.50) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL5504001 | 0.87 | ALDH1A1 (0.50) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11346990 | 0.87 | ALDH1A1 (0.50) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL5508077 | 0.87 | ALDH1A1 (0.50) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11568661 | 0.87 | ALDH1A1 (0.50) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11596614 | 0.86 | ALDH1A1 (0.57) | CNR2ALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL11596464 | 0.86 | ALDH1A1 (0.57) | CNR2ALDH1A1L3MBTL1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |