Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527071 | 0.99 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL11595283 | 0.88 | CNR2 (0.54) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL11595563 | 0.88 | CNR2 (0.54) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL11633948 | 0.86 | CNR2 (0.50) | ALDH1A1MAPTLMNACNR2MEN1 | |
| SCHEMBL5508282 | 0.85 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL11635788 | 0.85 | CNR2 (0.52) | ALDH1A1LMNACNR2KMT2ATDP1 | |
| SCHEMBL11568661 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL5504001 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL5508077 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTTP53LMNA | |
| SCHEMBL11346990 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |