Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 3/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 4/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649650 | 0.88 | ALDH1A1 (0.52) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL11616837 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL152904 | 0.78 | NT5E (0.50) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL29961913 | 0.78 | NT5E (0.50) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL30726813 | 0.78 | NT5E (0.50) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL10133622 | 0.77 | CA1 (0.45) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL30091340 | 0.76 | TTR (0.65) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL147723 | 0.76 | TTR (0.65) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL29459902 | 0.76 | TTR (0.65) | ALDH1A1TDP1HSD17B10CASP1CASP7 | |
| SCHEMBL10649404 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TDP1HSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |