Sugi Predict

Sugi Predict / Compounds / SCHEMBL4649650

SCHEMBL4649650

SCHEMBL4649650

Nc1cc(S(=O)(=O)O)c2cc(N)cc(S(=O)(=O)O)c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.52
▸ TDP1 Q9NUW8 5/20 0.52
▸ HSD17B10 Q99714 5/20 0.52
▸ CASP1 P29466 1/20 0.52
▸ CASP7 P55210 1/20 0.52
▸ NT5E P21589 4/20 0.44
▸ RAPGEF4 Q8WZA2 1/20 0.44
▸ TTR P02766 1/20 0.42
▸ CASP6 P55212 4/20 0.42
▸ MAPT P10636 3/20 0.42
▸ RECQL P46063 3/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ POLB P06746 2/20 0.42
▸ GAA P10253 2/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ NSD2 O96028 2/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ APOBEC3A P31941 1/20 0.42
▸ APOBEC3G Q9HC16 1/20 0.42
▸ TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616837 0.98 ALDH1A1 (0.50) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL152904 0.89 NT5E (0.50) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL29961913 0.89 NT5E (0.50) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL30726813 0.89 NT5E (0.50) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL11596137 0.88 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL29459902 0.86 TTR (0.65) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL147723 0.86 TTR (0.65) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL30091340 0.86 TTR (0.65) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL10649404 0.84 ALDH1A1 (0.41) ALDH1A1TDP1HSD17B10CASP1CASP7
SCHEMBL30903869 0.84 TTR (0.62) ALDH1A1TDP1HSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4801693-A DYEING WOOL, CELLULOSE, OR COTTON BASF AKTIENGESELLSCHAFT (DE) 1989-01-31 — — US claimed
CN-105683297-B Acid dyes, and its preparation method and application 德司达染料分销有限公司 2018-08-07 — — CN disclosed
EP-3063232-B1 ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2017-05-17 — — EP disclosed
US-9650516-B2 Acid dyes, process for the production thereof and their use DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2017-05-16 — — US disclosed
US-20160257816-A1 ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-09-08 — — US disclosed
EP-3063232-A1 ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE DyStar Colours Distribution GmbH (DE) 2016-09-07 — — EP disclosed
WO-2015062928-A1 ACID DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-05-07 — — WO disclosed
EP-2868709-A1 Metal free acid dyes, process for the production thereof and their use DyStar Colours Distribution GmbH (DE) 2015-05-06 — — EP disclosed
US-20090056587-A1 Compound, Ink, Process And Use FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-03-05 — — US disclosed
US-20090056587-A1 Compound, Ink, Process And Use FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-03-05 — — US disclosed
US-4204056-A Process and intermediates for preparing fiber-reactive phthalocyanine dyes CASSELLA AKTIENGESELLSCHAFT (DE) 1980-05-20 — — US disclosed
US-4191686-A FROM SULFONYL HALIDE SUBSTITUTED PARENT BY AMIDATION WITH AROMATIC DIAMINE, DIAZOTIZING, COUPLING TO KETO SUCCINIC ESTER, CYCLIZING, COUPLING TO REACTIVE MOIETY CASSELLA AKTIENGESELLSCHAFT (DE) 1980-03-04 — — US disclosed
US-4191687-A Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-04 — — US disclosed
EP-0001614-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation CASSELLA Aktiengesellschaft (DE) 1979-05-02 — — EP disclosed
EP-0001629-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-05-02 — — EP disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 — — EP disclosed
US-4145340-A WATER-SOLUBLE REACTIVE MONOAZO DYE CONTAINING A NONYLPHENOXY, CHLOROTRIAZINE GROUP IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-03-20 — — US disclosed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 — — US disclosed
US-4120892-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-10-17 — — US disclosed
US-4066389-A SULFOPHENYLAMINO CONTAINING TETRAREACTIVE TRIAZINE DISAZO DYESTUFFS AND DYESTUFF COMPOSITIONS THEREOF CIBA-GEIGY CORPORATION (US) 1978-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090056587-A1 Compound, Ink, Process And Use JAK1, RB1, CCNA1 ALDH1A1 247/4885TDP1 1118/4885HSD17B10 2332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.