Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743428 | 0.78 | KDM4E (0.45) | KDM4ECYP3A4MAPTFFAR2EPHX2 | |
| SCHEMBL11544529 | 0.76 | KDM4E (0.40) | ARKDM4ETP53CYP3A4MAPT | |
| SCHEMBL11595129 | 0.75 | KDM4E (0.39) | ARKDM4ETP53CYP3A4MAPT | |
| SCHEMBL11536828 | 0.75 | KDM4E (0.39) | ARKDM4ETP53CYP3A4MAPT | |
| SCHEMBL7091214 | 0.75 | LMNA (0.50) | EPHX2FAAHCES1 | |
| SCHEMBL11594989 | 0.74 | KDM4E (0.38) | ARKDM4ETP53CYP3A4MAPT | |
| SCHEMBL11593235 | 0.73 | KDM4E (0.38) | ARKDM4ETP53CYP3A4MAPT | |
| SCHEMBL11593210 | 0.73 | ADORA1 (0.43) | — | |
| SCHEMBL11594533 | 0.73 | KMT2A (0.36) | ARKMT2AFAAHCES1 | |
| SCHEMBL30846731 | 0.72 | AR (0.56) | ARKDM4ETP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |