Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596585 | 0.83 | KDM4E (0.36) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11595474 | 0.78 | CCR2 (0.40) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11596174 | 0.75 | AR (0.40) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11536828 | 0.73 | KDM4E (0.39) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11593178 | 0.72 | TP53 (0.38) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11544529 | 0.71 | KDM4E (0.40) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11540052 | 0.71 | CNR2 (0.37) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11594989 | 0.69 | KDM4E (0.38) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11593235 | 0.68 | KDM4E (0.38) | KDM4ETP53CYP3A4MAPTALOX15 | |
| SCHEMBL11540702 | 0.68 | KDM4E (0.44) | KDM4ETP53CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |